| Primary Identifier | MGI:1929092 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 56275 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA binding activity and splicing factor binding activity. Involved in centriole assembly and mRNA splicing, via spliceosome. Acts upstream of or within apoptotic process; gastrulation; and regulation of response to DNA integrity checkpoint signaling. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Predicted to be active in nuclear speck. Is expressed in central nervous system; limb; liver; sensory organ; and stomach epithelium. Orthologous to several human genes including RBM14 (RNA binding motif protein 14). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality with impaired gastrulation, reduced cell density in the epiblast and mesoderm, and absent allantois, chorion, amnion, and primitive streak. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
