| Primary Identifier | MGI:107576 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 20469 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity. Acts upstream of or within regulation of cell cycle. Predicted to be located in several cellular components, including endomembrane system; nucleus; and perinuclear region of cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Is expressed in several structures, including genitourinary system; heart; immune system; liver; and lung. Used to study chronic myeloid leukemia. Orthologous to human SIPA1 (signal-induced proliferation-associated 1). PHENOTYPE: Homozygous null mice display chronic myelocytic leukemia in either the chronic phase or blast crisis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
