| Primary Identifier | MGI:1346880 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 26403 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP binding activity; JUN kinase kinase kinase activity; and enzyme binding activity. Predicted to be involved in several processes, including JNK cascade; cell cycle G1/S phase transition; and positive regulation of MAPK cascade. Predicted to be located in microtubule. Predicted to be active in centrosome and cytoplasm. Is expressed in blood vessel; brain; and embryo. Orthologous to human MAP3K11 (mitogen-activated protein kinase kinase kinase 11). PHENOTYPE: Homozygotes for a targeted or spontaneous mutation display a pattern of dark red stripes of thin dorsal epithelium during pre-wean development, and necrotic dental pulp has been reported for the spontaneous mutant. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
