Primary Identifier | MGI:1921731 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 74481 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to protozoan and myeloid dendritic cell differentiation. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in brain; central nervous system; dorsal root ganglion; lung; and spinal cord. Orthologous to human BATF2 (basic leucine zipper ATF-like transcription factor 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to parasitic infection induced morbidity/mortality. [provided by MGI curators] |