Primary Identifier | MGI:1923913 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 622554 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Involved in homologous chromosome pairing at meiosis and meiotic attachment of telomere to nuclear envelope. Acts upstream of or within double-strand break repair involved in meiotic recombination; oogenesis; and spermatogenesis. Located in chromosome, telomeric region and nuclear inner membrane. Is expressed in several structures, including gonad; liver; lung; muscle tissue; and spleen. Orthologous to human MAJIN (membrane anchored junction protein). PHENOTYPE: Mice homozygous for a null allele lack sperm and oocyte. [provided by MGI curators] |