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Protein Coding Gene : Prpf19 pre-mRNA processing factor 19
Primary Identifier  MGI:106247 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  28000
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in proteasomal protein catabolic process. Acts upstream of or within lipid biosynthetic process and positive regulation of mRNA splicing, via spliceosome. Located in nucleus. Is expressed in several structures, including extraembryonic component and genitourinary system. Orthologous to human PRPF19 (pre-mRNA processing factor 19).
PHENOTYPE: Mice homozygous for a null allele die prior to implantation and have defective cell proliferation. [provided by MGI curators]
  • synonyms:
  • Prp19,
  • pre-mRNA processing factor 19,
  • DNA segment, Chr 19, Wayne State University 55, expressed,
  • MGI:2147181,
  • MGD-MRK-33939,
  • expressed sequence AA617263,
  • Snev,
  • MGI:2147631,
  • AL024362,
  • D19Wsu55e,
  • PSO4,
  • PRP19/PSO4 homolog (S. cerevisiae),
  • Prpf19,
  • AA617263,
  • expressed sequence AL024362
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