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Protein Coding Gene : Lpxn leupaxin
Primary Identifier  MGI:2147677 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  107321
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables transcription coregulator activity. Involved in negative regulation of B cell receptor signaling pathway and regulation of cell adhesion mediated by integrin. Located in focal adhesion; nucleus; and podosome. Is expressed in central nervous system; genitourinary system; and thymus. Orthologous to human LPXN (leupaxin).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased circulation glucose levels and impaired plasma cell differentiation after stimulation with LPS. [provided by MGI curators]
  • synonyms:
  • Lpxn,
  • AV278559,
  • RIKEN cDNA 4933402K05 gene,
  • RIKEN cDNA A530083L21 gene,
  • 4933402K05Rik,
  • leupaxin,
  • MGI:2442455,
  • expressed sequence AV278559,
  • A530083L21Rik
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