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Protein Coding Gene : Pabir1 PP2A A alpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1

Primary Identifier  MGI:1915284 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  68034
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in mitotic G2/M transition checkpoint; positive regulation of cell growth; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nuclear body. Is expressed in embryo. Orthologous to human PABIR1 (PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1).
PHENOTYPE: Mice homozygous for a null allele show embryonic lethality from E9.5-E12.5 with growth defects, open anterior neural folds, somite formation and turning defects and severe cardiovascular development defects. [provided by MGI curators]
  • synonyms:
  • Pabir1,
  • 2410124L17Rik,
  • family with sequence similarity 122, member A,
  • MGI:1920926,
  • PP2A A alpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1,
  • RIKEN cDNA 2900009I07 gene,
  • Fam122a,
  • RIKEN cDNA 2410124L17 gene,
  • ENSMUSG00000051082,
  • predicted gene 9849,
  • MGI:7414057,
  • MGI:3708647,
  • 2900009I07Rik,
  • Gm9849,
  • predicted gene, ENSMUSG00000051082

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