| Primary Identifier | MGI:2385089 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 226043 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activity and zinc chaperone activity. Involved in intracellular zinc ion homeostasis; kidney development; and protein maturation. Located in nucleus. Is expressed in metanephros and vibrissa. Used to study CAKUT. Orthologous to several human genes including ZNG1A (Zn regulated GTPase metalloprotein activator 1A); ZNG1C (Zn regulated GTPase metalloprotein activator 1C); and ZNG1E (Zn regulated GTPase metalloprotein activator 1E). PHENOTYPE: Mice homozygous for a null allele exhibit hydronephrosis, hydroureter, and double ureter, all CAKUT phentoypes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
