| Primary Identifier | MGI:105083 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 20510 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables amino acid transmembrane transporter activity; identical protein binding activity; and monoatomic anion channel activity. Involved in several processes, including cell surface receptor signaling pathway; learning or memory; and nervous system development. Acts upstream of or within several processes, including behavioral fear response; cellular response to bisphenol A; and regulation of protein metabolic process. Located in endosome membrane; membrane raft; and plasma membrane. Is active in several cellular components, including Schaffer collateral - CA1 synapse; apical plasma membrane; and recycling endosome. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system gland; and nervous system. Used to study dicarboxylic aminoaciduria and low tension glaucoma. Human ortholog(s) of this gene implicated in dicarboxylic aminoaciduria and schizophrenia 18. Orthologous to human SLC1A1 (solute carrier family 1 member 1). PHENOTYPE: Mice homozygous for disruptions in this gene display reduced locomotor activity and excessive excretion of glutamate and aspartate. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
