Primary Identifier | MGI:1923505 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 76073 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone H2AK119 ubiquitin ligase activity. Involved in random inactivation of X chromosome. Part of PcG protein complex. Colocalizes with X chromosome. Is expressed in bladder; central nervous system; embryo; heart; and ureter. Orthologous to human PCGF5 (polycomb group ring finger 5). PHENOTYPE: Bone marrow cells from mice homozygous for a conditional allele exhibit normal hematopoietic and progenitor cell function. [provided by MGI curators] |