Primary Identifier | MGI:2147538 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 107182 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP-dependent activity, acting on DNA and transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Is expressed in several structures, including genitourinary system. Orthologous to human BTAF1 (B-TFIID TATA-box binding protein associated factor 1). PHENOTYPE: Embryos homozygous for a gene-trapped allele display growth retardation. Embryos homozygous for an ENU-induced allele show growth retardation, edema, abnormal blood circulation, myocardial trabeculae hypoplasia, and delayed head and brain development. [provided by MGI curators] |