| Primary Identifier | MGI:2135874 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 93721 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables carboxypeptidase activity. Predicted to be involved in several processes, including bradykinin catabolic process; protein processing; and response to glucocorticoid. Predicted to be active in extracellular space. Is expressed in several structures, including gonad; gut; liver; neural tube; and yolk sac. Human ortholog(s) of this gene implicated in carboxypeptidase N deficiency. Orthologous to human CPN1 (carboxypeptidase N subunit 1). PHENOTYPE: Mice homozygous for a knock-out allele are highly susceptible to lethal anaphylactic shock caused by acute complement activation when administered cobra venom factor or C5a complement. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
