| Primary Identifier | MGI:1888897 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 226143 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable arachidonate epoxygenase activity; heme binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in epoxygenase P450 pathway; icosanoid biosynthetic process; and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in metanephros; stomach; submandibular gland; and testis. Orthologous to human CYP2C23P (cytochrome P450 family 2 subfamily C member 23, pseudogene). PHENOTYPE: Mice homozygous for a gene trapped allele show reduced proliferative and tubulogenic responses in lung endothelial cells, decreased tumor angiogenesis and growth of induced tumors, and high potassium-induced hypertension with decreased urinary sodium excretion and increased plasma sodium levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
