Primary Identifier | MGI:109485 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 22423 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within negative regulation of gene expression and positive regulation of gene expression. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cochlea; eye; future brain; head mesenchyme; and nervous system. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Orthologous to human WNT8B (Wnt family member 8B). PHENOTYPE: Mice homozygous for a null allele are viable and healthy with no evidence of hippocampal or hypothalamic defects and normal cell proliferation in the neurogenic region of the adult dentate gyrus. [provided by MGI curators] |