Primary Identifier | MGI:1889000 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 56626 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-directed DNA polymerase activity. Predicted to be involved in DNA metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in nucleus and site of double-strand break. Is expressed in muscle tissue; retina; and seminiferous tubule. Orthologous to human POLL (DNA polymerase lambda). PHENOTYPE: Mice homozygous for a knock-out allele exhibit defective heavy chain rearrangement. See also the Dpcd gene for mutations that affect both of these overlapping genes. [provided by MGI curators] |