Primary Identifier | MGI:1889000 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 56626 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables DNA-directed DNA polymerase activity. Predicted to be involved in DNA metabolic process. Predicted to act upstream of or within DNA repair and DNA replication. Predicted to be located in nucleoplasm. Predicted to be active in nucleus and site of double-strand break. Is expressed in muscle tissue; retina; and seminiferous tubule. Orthologous to human POLL (DNA polymerase lambda). PHENOTYPE: Mice homozygous for a knock-out allele exhibit defective heavy chain rearrangement. See also the Dpcd gene for mutations that affect both of these overlapping genes. [provided by MGI curators] |