| Primary Identifier | MGI:1354698 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 30838 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within cartilage development; embryonic digit morphogenesis; and positive regulation of mesenchymal cell proliferation. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in brain; diencephalon roof plate; midbrain ventricular layer; and midbrain-hindbrain junction. Orthologous to human FBXW4 (F-box and WD repeat domain containing 4). PHENOTYPE: Homozygotes for a spontaneous null mutation lack feet except for a single fused digit and die prenatally. Heterozygotes, in the presence of a recessive modifying allele, show loss of digits, frequently with fused metatarsal and metacarpal bones. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
