Primary Identifier | MGI:2442144 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 226182 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity and promoter-specific chromatin binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly; mRNA transcription by RNA polymerase II; and positive regulation of transcription initiation by RNA polymerase II. Located in nucleus. Is expressed in embryo and tail. Orthologous to human TAF5 (TATA-box binding protein associated factor 5). PHENOTYPE: Mice homozygous for a knock-out allele arrest before progressing to an egg-cylinder stage and show empty deciduae, failure of embryo implantation, aberrant lineage specification within the inner cell mass, and peri-implantation lethality. [provided by MGI curators] |