| Primary Identifier | MGI:2685183 | Organism | mouse, laboratory |
| Chromosome | 19 | NCBI Gene Number | 240672 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable MAP kinase tyrosine/serine/threonine phosphatase activity. Predicted to be involved in several processes, including endoderm formation; protein dephosphorylation; and regulation of blood circulation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; cerebellum; lung; retina layer; and telencephalon mantle layer. Orthologous to human DUSP5 (dual specificity phosphatase 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased proliferation and apoptosis and altered metabolic profiles in T cells. Mice homozygous for other null alleles exhibit altered eosinophilic response to parasicitc infection and increased susceptibility to induced tumors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
