Primary Identifier | MGI:106025 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 73707 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables guanylate cyclase activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Located in external side of plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; immune system; liver; and musculature. Orthologous to human GUCY2GP (guanylate cyclase 2G, pseudogene). PHENOTYPE: Mice homozygous for a null mutation are viable and fertile with no gross abnormalities and are protected against acute ischemia induced renal injury. [provided by MGI curators] |