Primary Identifier | MGI:2652824 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 414758 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and protein-macromolecule adaptor activity. Acts upstream of or within several processes, including face morphogenesis; smooth muscle cell migration; and vasculogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in bladder; central nervous system; testis; and ureter. Orthologous to several human genes including ZNF234 (zinc finger protein 234); ZNF254 (zinc finger protein 254); and ZNF28 (zinc finger protein 28). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit some postnatal lethality, altered craniofacial structures, kidney defects, embryonic hemorrhaging and cell migration defects. [provided by MGI curators] |