Primary Identifier | MGI:1202298 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 18108 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable glycylpeptide N-tetradecanoyltransferase activity and peptidyl-lysine N6-myristoyltransferase activity. Predicted to be involved in N-terminal peptidyl-glycine N-myristoylation and protein localization to membrane. Predicted to act upstream of or within N-terminal protein myristoylation. Predicted to be located in Golgi apparatus and plasma membrane. Predicted to be active in cytosol. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and liver. Orthologous to human NMT2 (N-myristoyltransferase 2). PHENOTYPE: Mice homozygous for a conditional allele knocked out in T cells exhibit reduced T cell, double positive T cell and single positive T cell numbers. [provided by MGI curators] |