| Primary Identifier | MGI:1353592 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 30963 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable enzyme binding activity; hydroxyapatite binding activity; and very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity. Acts upstream of or within myotube differentiation; regulation of G1/S transition of mitotic cell cycle; and regulation of G2/M transition of mitotic cell cycle. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; embryo mesenchyme; lung; musculature; and nervous system. Human ortholog(s) of this gene implicated in congenital myopathy. Orthologous to human HACD1 (3-hydroxyacyl-CoA dehydratase 1). PHENOTYPE: Homozygous knockout leads to decreased body size and weight and reduced skeletal muscle weight. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
