Primary Identifier | MGI:1861354 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 54519 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell and positive regulation of cell adhesion. Located in cytosol and plasma membrane. Part of T cell receptor complex. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system; liver; and molar. Orthologous to human APBB1IP (amyloid beta precursor protein binding family B member 1 interacting protein). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and healthy with no apparent defects in platelet integrin activation and function, hemostasis, or arterial thrombus formation. [provided by MGI curators] |