Primary Identifier | MGI:1919340 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 72090 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nucleoside diphosphate phosphatase activity and ribonucleoside triphosphate phosphatase activity. Acts upstream of or within nucleoside diphosphate biosynthetic process and nucleoside monophosphate biosynthetic process. Located in membrane. Is expressed in esophagus; intestine; lung; and reproductive system. Orthologous to human ENTPD8 (ectonucleoside triphosphate diphosphohydrolase 8). PHENOTYPE: Mice homozygous for a null allele display elevated colonic ATP levels and increased sensitivity to induced colitis. [provided by MGI curators] |