Primary Identifier | MGI:2443597 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 227615 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in intracellular calcium ion homeostasis and spermatogenesis. Predicted to be located in endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; and lysosomal membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human TMEM203 (transmembrane protein 203). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced body weight, abnormal calcium homeostasis, arreasted spermiation, azoospermia, male infertility and reduced total litter numbers in female mice. [provided by MGI curators] |