Primary Identifier | MGI:1922704 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 75454 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including calcium channel inhibitor activity; protein histidine phosphatase activity; and transmembrane transporter binding activity. Involved in positive regulation of cell motility. Located in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Orthologous to human PHPT1 (phosphohistidine phosphatase 1). PHENOTYPE: Homozygous knockout leads to neonatal hyperinsulinemic hypoglycemia and to impaired glucose tolerance in adult mice. [provided by MGI curators] |