| Primary Identifier | MGI:2183102 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 192166 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable flavin adenine dinucleotide binding activity; folic acid binding activity; and sarcosine dehydrogenase activity. Predicted to be involved in sarcosine catabolic process and tetrahydrofolate interconversion. Located in mitochondrion. Is expressed in brain; future brain; hepatic primordium; and liver. Human ortholog(s) of this gene implicated in sarcosinemia. Orthologous to human SARDH (sarcosine dehydrogenase). PHENOTYPE: Mice homozygous for a null allele reduced body weight, impaired spatial working memory, reduced hippocampal sacosine and formaldehyde levels, and reduced NMDA currents. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
