Primary Identifier | MGI:2442186 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 227682 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable pseudouridine synthase activity. Predicted to be involved in mRNA pseudouridine synthesis and positive regulation of mitochondrial translation. Predicted to be located in mitochondrion and ribonucleoprotein granule. Is expressed in trunk unsegmented mesenchyme. Orthologous to human TRUB2 (TruB pseudouridine synthase family member 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal trophoblast layer formation and complete embryonic lethality during organogenesis. [provided by MGI curators] |