| Primary Identifier | MGI:1347347 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 26569 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables oleoyl-CoA ligase activity and very long-chain fatty acid-CoA ligase activity. Involved in glucose import in response to insulin stimulus; long-chain fatty acid import into cell; and negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity. Acts upstream of or within several processes, including fatty acid metabolic process; fatty acid transport; and skin development. Located in brush border membrane; endoplasmic reticulum; and microvillus. Is expressed in several structures, including alimentary system; eye; nervous system; skin; and urinary system. Used to study restrictive dermopathy. Orthologous to human SLC27A4 (solute carrier family 27 member 4). PHENOTYPE: Homozygous mutant mice are not viable. While mice of one mutant line die during early development, mice of other mutant lines die at birth exhibiting abnormal skin. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
