| Primary Identifier | MGI:2139395 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 99412 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables importin-alpha family protein binding activity. Involved in asymmetric cell division and meiotic spindle assembly. Acts upstream of or within Golgi localization and positive regulation of axonogenesis. Located in Golgi apparatus; perinuclear region of cytoplasm; and spindle pole. Is expressed in several structures, including brain; eye; gonad; musculoskeletal system; and unsegmented mesenchyme. Orthologous to human GOLGA2 (golgin A2). PHENOTYPE: Homozygotes for a null allele show premature death, developmental delay, ataxia, Purkinje neuron loss, and male infertility with globozoospermia and lack of acrosome formation. Homozygotes for a different null allele show partial prenatal lethality and autophagy-induced liver and lung fibrosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
