Primary Identifier | MGI:1341894 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 20448 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Predicted to be involved in ganglioside biosynthetic process and oligosaccharide metabolic process. Predicted to be located in Golgi membrane. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system; integumental system; and sensory organ. Orthologous to human ST6GALNAC4 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4). PHENOTYPE: Mice homozygous for a null allele exhibit no abnormal phenotype. Double homozygotes lacking St6galnac3 and St6galnac4 exhibit lymph node hemorrhage associated with structural disruption of high endothelial venule. [provided by MGI curators] |