Primary Identifier | MGI:104626 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 20744 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables double-stranded RNA binding activity; microtubule binding activity; and single-stranded RNA binding activity. Acts upstream of or within cell motility; mechanosensory behavior; and spermatid development. Located in manchette. Is expressed in central nervous system; dorsal root ganglion; metanephros; sensory organ; and trigeminal nerve. Orthologous to human STRBP (spermatid perinuclear RNA binding protein). PHENOTYPE: Mice homozygous for a gene trap insertion exhibit premature death, a reduced body size and an abnormal clutching reflex. Minor brain abnormalities and spermatogenesis defects were also noted. [provided by MGI curators] |