Primary Identifier | MGI:1891638 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 59126 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein serine/threonine kinase activity. Predicted to be involved in chromosome segregation; protein phosphorylation; and regulation of mitotic metaphase/anaphase transition. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human NEK6 (NIMA related kinase 6). PHENOTYPE: No significant homozygous or heterozygous mutant phenotype was detected in a high throughput screen of a targeted mutation, however these homozygotes exhibit an increased response of the heart to induced stress, with aggravated cardiac hypertrophy. [provided by MGI curators] |