Primary Identifier | MGI:2661081 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 269275 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP binding activity; BMP receptor binding activity; and activin binding activity. Acts upstream of or within several processes, including negative regulation of insulin secretion; response to dietary excess; and response to insulin. Predicted to be located in cell surface. Predicted to be part of activin receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including adipose tissue; adrenal gland; alimentary system; brain; and genitourinary system. Orthologous to human ACVR1C (activin A receptor type 1C). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile, and overtly normal with no apparent left-right patterning abnormalities or organogenesis defects. [provided by MGI curators] |