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Protein Coding Gene : Dapl1 death associated protein-like 1

Primary Identifier  MGI:1923997 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  76747
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ribosome binding activity; translation initiation factor binding activity; and translation repressor activity. Involved in negative regulation of CD8-positive, alpha-beta T cell activation. Acts upstream of or within cell population proliferation and gene expression. Is active in nucleus. Is expressed in 1-cell stage embryo; cap mesenchyme; eye; integumental system; and tongue epithelium. Orthologous to human DAPL1 (death associated protein like 1).
PHENOTYPE: Mice homozygous for a null allele exhibit increased proliferation of retinal pigment epithelial cells forming multiple layers. [provided by MGI curators]
  • synonyms:
  • death associated protein-like 1,
  • 2310032F03Rik,
  • RIKEN cDNA 2310032F03 gene,
  • EEDA,
  • Dapl1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For