Primary Identifier | MGI:1923997 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 76747 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ribosome binding activity; translation initiation factor binding activity; and translation repressor activity. Involved in negative regulation of CD8-positive, alpha-beta T cell activation. Acts upstream of or within cell population proliferation and gene expression. Is active in nucleus. Is expressed in 1-cell stage embryo; cap mesenchyme; eye; integumental system; and tongue epithelium. Orthologous to human DAPL1 (death associated protein like 1). PHENOTYPE: Mice homozygous for a null allele exhibit increased proliferation of retinal pigment epithelial cells forming multiple layers. [provided by MGI curators] |