Primary Identifier | MGI:2442798 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 241452 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity and steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in 9-cis-retinoic acid biosynthetic process; androgen metabolic process; and progesterone metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human DHRS9 (dehydrogenase/reductase 9). PHENOTYPE: Mice homozygous for a null allele exhibit reduced LTB4 ad RvD1 dehydrogenase activities in the skin, lung, and tracheal microsomes. [provided by MGI curators] |