| Primary Identifier | MGI:2448580 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 329421 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microfilament motor activity and protein serine/threonine kinase activity. Involved in inner ear morphogenesis; regulation of actin filament length; and sensory perception of sound. Acts upstream of or within positive regulation of filopodium assembly and protein phosphorylation. Located in filopodium tip; photoreceptor inner segment; and photoreceptor outer segment. Is active in stereocilium tip. Is expressed in several structures, including genitourinary system; nervous system; and submandibular gland. Orthologous to human MYO3B (myosin IIIB). PHENOTYPE: Mice homozygous for a null allele show a subtle defect in stereocilia staircase step spacing in the extrastriolar regions of the utricle, but have normal hearing thresholds and no overt vestibular dysfunction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
