| Primary Identifier | MGI:94901 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 13390 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in negative regulation of photoreceptor cell differentiation; positive regulation of amacrine cell differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including forebrain development; negative regulation of Notch signaling pathway; and negative regulation of oligodendrocyte differentiation. Located in nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and sensory organ. Orthologous to human DLX1 (distal-less homeobox 1). PHENOTYPE: Homozygous null mutants show morphogenetic abnormalities in first and second branchial arch-derived proximal skeletal and soft tissue structures; in double mutants with a Dlx2 null allele, maxillary molar teeth are missing. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
