| Primary Identifier | MGI:3036251 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 241489 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 3',5'-cyclic-nucleotide phosphodiesterase activity and cGMP binding activity. Predicted to be involved in cAMP-mediated signaling; negative regulation of cAMP-mediated signaling; and negative regulation of cGMP-mediated signaling. Predicted to be located in perikaryon. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; genitourinary system; and skeleton. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease 2. Orthologous to human PDE11A (phosphodiesterase 11A). PHENOTYPE: Mice homozygous for a null allele have enlarged lateral ventricles and exhibit abnormal behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
