Primary Identifier | MGI:2664111 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 241516 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to act upstream of or within with a positive effect on protein localization to cilium and sperm axoneme assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in spermatogenic failure 34. Orthologous to human FSIP2 (fibrous sheath interacting protein 2). PHENOTYPE: Homozygous knockout leads to male sterility owing to sperm flagellum anomalies caused by the absence of the fibrous sheath. [provided by MGI curators] |