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Protein Coding Gene : Tmx2 thioredoxin-related transmembrane protein 2

Primary Identifier  MGI:1914208 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  66958
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable disulfide oxidoreductase activity and identical protein binding activity. Predicted to be involved in brain development. Predicted to be located in endoplasmic reticulum membrane and mitochondrion. Predicted to be active in mitochondria-associated endoplasmic reticulum membrane contact site. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; hemolymphoid system; and nervous system. Orthologous to human TMX2 (thioredoxin related transmembrane protein 2).
PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality before implantation with abnormal morula morphology, increased cell death, and failure of blastocyst formation. [provided by MGI curators]
  • synonyms:
  • thioredoxin domain containing 14,
  • Txndc14,
  • AA589631,
  • 2310042M24Rik,
  • RIKEN cDNA 2310042M24 gene,
  • thioredoxin-related transmembrane protein 2,
  • MGI:2146774,
  • Tmx2,
  • expressed sequence AA589631

Features --> Cross References

Genome

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4 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

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Mouse features --> Functions (GO terms)

Homology

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Disease

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