Primary Identifier | MGI:1915928 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 68678 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including calmodulin binding activity; protein domain specific binding activity; and protein phosphatase 1 binding activity. Involved in negative regulation of DNA-templated transcription and positive regulation of vasoconstriction. Acts upstream of or within several processes, including peptidyl-serine phosphorylation; response to activity; and vasoconstriction. Located in I band; M band; and nucleus. Is expressed in several structures, including aorta; diaphragm; genitourinary system; intestine; and skeletal muscle. Orthologous to human SMTNL1 (smoothelin like 1). PHENOTYPE: Mice homozygous for a null allele exhibit vascular and muscular adaptations normally found in exercised animals as well as increased exercise endurance. [provided by MGI curators] |