| Primary Identifier | MGI:1196429 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 51897 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in several processes, including macroautophagy; regulation of protein lipidation; and response to mitochondrial depolarisation. Located in cytosol and phagophore assembly site. Part of Atg1/ULK1 kinase complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human ATG13 (autophagy related 13). PHENOTYPE: Mice homozygous for a null mutation display lethality during fetal growth and development with thinning of the cardiac ventricular wall. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
