Primary Identifier | MGI:1278339 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 104418 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP-dependent diacylglycerol kinase activity and enzyme inhibitor activity. Involved in several processes, including glycerolipid metabolic process; lipid phosphorylation; and maintenance of postsynaptic density structure. Acts upstream of or within negative regulation of Ras protein signal transduction. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human DGKZ (diacylglycerol kinase zeta). PHENOTYPE: The T cell response is enhanced in homozygous mutant mice, which showed a robust response to viral infection. [provided by MGI curators] |