Primary Identifier | MGI:3045306 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 241624 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity and protein homodimerization activity. Involved in piRNA processing. Part of PET complex. Is expressed in testis. Orthologous to human EXD1 (exonuclease 3'-5' domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele are fertile and viable, but exhibit defective biogenesis of antisense piRNAs and activation of transposons in male germ cells. [provided by MGI curators] |