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Protein Coding Gene : Rtf1 RTF1, Paf1/RNA polymerase II complex component
Primary Identifier  MGI:1309480 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  76246
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity and single-stranded DNA binding activity. Involved in several processes, including endodermal cell fate commitment; negative regulation of transcription by RNA polymerase II; and stem cell population maintenance. Acts upstream of or within blastocyst growth. Located in nucleolus. Part of Cdc73/Paf1 complex. Is expressed in several structures, including brain and retina nuclear layer. Used to study dilated cardiomyopathy. Orthologous to human RTF1 (RTF1 homolog, Paf1/RNA polymerase II complex component).
  • synonyms:
  • RTF1, Paf1/RNA polymerase II complex component,
  • gene trap locus 7,
  • MGI:2139096,
  • Rtf1,
  • MGI:1925759,
  • MGI:2139215,
  • RIKEN cDNA 2900005O08 gene,
  • Gtl7,
  • AI853581,
  • MGI:1923496,
  • expressed sequence AI853581,
  • expressed sequence AW553985,
  • MGI:2139393,
  • AW553985,
  • expressed sequence AU043144,
  • 2900005O08Rik,
  • RIKEN cDNA 6530416A09 gene,
  • 6530416A09Rik,
  • AU043144
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2 Involved In Mutations

Trail: ProteinCodingGene

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