Primary Identifier | MGI:1345282 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 22785 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables zinc ion transmembrane transporter activity. Involved in zinc ion transmembrane transport. Acts upstream of or within zinc export across plasma membrane. Predicted to be located in endosome membrane and late endosome. Predicted to be active in plasma membrane. Is expressed in medulla oblongata basal plate mantle layer and placenta. Orthologous to human SLC30A4 (solute carrier family 30 member 4). PHENOTYPE: Homozygous mutant dams produce zinc-deficient milk that is lethal to all nursing pups. Pleiotropic defects observed in mutant males and females include otolith degeneration, impaired motor coordination, alopecia, and dermatitis. [provided by MGI curators] |