| Primary Identifier | MGI:2387661 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 214968 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables receptor ligand activity and semaphorin receptor binding activity. Involved in T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell and semaphorin-plexin signaling pathway. Acts upstream of or within negative regulation of smooth muscle cell migration; positive regulation of smooth muscle cell migration; and ventricular system development. Located in collagen-containing extracellular matrix. Is expressed in several structures, including central nervous system; gut mesenchyme; retina; spinal ganglion or nerve; and vascular element. Orthologous to human SEMA6D (semaphorin 6D). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal dendritic cell trafficking and antigen-specific T cell priming. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
